This is a known fact that Covid-19 infection leads to severe pneumonia. But the mechanism behind this is still unknown and researchers are trying to find out the molecular mechanism behind this. It is still unknown how Covid-19 can lead to respiratory failure. Respiratory failure often leads to renal and myocardial health issues. There also has been observed a prothrombotic phenotype in Covid-19 patients.
Research published in the journal Circulation has reported a suitable mechanism for increased blood clots in Covid-19 patients.
SARS-CoV-2 is a novel coronavirus that has no possible treatment and cure at the moment. The previous drugs and therapies may not work for this new virus. The possible reason behind this is that the virus has somehow affected the patient differently and has a unique molecular mechanism to damage the body. This is why it is important to understand the mechanism behind Covid-19 so that new research can be done in the right direction.
This research has told us that if the coagulation is not rapid or too slow, there might be internal organ damage. Slow coagulation of the blood cells can lead to internal bleeding just like in the case of hemophilia. Too rapid or too much coagulation can lead to myocardial infarction or heart failure because of the blood blockage in the heart.
The research explains that there is increased blood coagulation in the Covid-19 patients that leads to organ failure.
The method they have used is flow cytometry. This technique revealed that there are elevated levels of neutrophils and platelets in Covid-19 patients as compared to the normal people that were treated as a control group during the studies.
This research concludes that there must be immunothrombotic dysregulation in Covid-19 patients. This is a kind of new marker to confirm the presence of the disease. This means, if a person has elevated blood coagulation in a patient, the patient is possibly suffering from Covid-19.